Pharmaceutical

3764-01-0

  • Product Name：2,4,6-Trichloropyrimidine
  • Molecular Formula：C4HCl3N2
  • Specifications：99%
  • Molecular Weight：183.424
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Product Details;

CasNo： 3764-01-0

Molecular Formula： C4HCl3N2

Appearance： clear colorless to yellowish liquid after melting

Reputable factory supply 2,4,6-Trichloropyrimidine 3764-01-0 in stock with high standard

  • Molecular Formula:C4HCl3N2
  • Molecular Weight:183.424
  • Appearance/Colour:clear colorless to yellowish liquid after melting 
  • Vapor Pressure:0.248mmHg at 25°C 
  • Melting Point:23-25 °C(lit.) 
  • Refractive Index:n20/D 1.57(lit.)  
  • Boiling Point:212.7 °C at 760 mmHg 
  • PKA:-7.14±0.30(Predicted) 
  • Flash Point:102.5 °C 
  • PSA：25.78000 
  • Density:1.641 g/cm3 
  • LogP:2.43680 

2,4,6-Trichloropyrimidine(Cas 3764-01-0) Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 80, p. 5481, 1958 DOI: 10.1021/ja01553a042

InChI:InChI=1/C4HCl3N2/c5-2-1-3(6)9-4(7)8-2/h1H

3764-01-0 Relevant articles

Synthesis of new organochalcogen (Se or Te) based multifunctional pyrimidine derivatives: X-ray structure determination of 2,4- bis(arylchalcogenyl)pyrimidine and 2-chloro-4,6-bis(arylchalcogenyl)pyrimidine compounds

Arora, Ekta,Bhasin,Mehta,Sharma, Nidhi,Bhasin,Jacob, Claus,Félix, Vítor,Neogi, Subhadip

, p. 316 - 322 (2014)

A new class of multinucleate pyrimidine ...

Synthesis of novel pyridine and pyrimidine derivatives as potential inhibitors of HIV-1 reverse transcriptase using palladium-catalysed C-N cross-coupling and nucleophilic aromatic substitution reactions

Changunda, Charles R.K.,Rousseau, Amanda L.,Basson, Adriaan E.,Bode, Moira L.

, p. 152 - 170 (2021/05/27)

Palladium-mediated cross-coupling reacti...

Invariant and Variable Supramolecular Self-Assembly in 6-Substituted Uracil Derivatives: Insights from X-ray Structures and Quantum Chemical Study

Abdelbaky, Mohammed S. M.,Al-Wahaibi, Lamya H.,Bysani, Sai Ramya Sree,El-Emam, Ali A.,Garcia-Granda, Santiago,Percino, M. Judith,Tawfik, Samar S.,Thamotharan, Subbiah

, p. 3234 - 3250 (2021/05/29)

In this study, three new 6-(arylthio)ura...

Efficient transposition of the sandmeyer reaction from batch to continuous process

D'Attoma, Joseph,Camara, Titi,Brun, Pierre Louis,Robin, Yves,Bostyn, Stéphane,Buron, Frédéric,Routier, Sylvain

, p. 44 - 51 (2017/11/30)

The transposition of Sandmeyer chlorinat...

3764-01-0 Process route

BARBITURIC ACID
67-52-7,944357-77-1

BARBITURIC ACID

2,4,6-trichloropyrimidine
3764-01-0

2,4,6-trichloropyrimidine

Conditions
Conditions Yield
93%
With 1-methyl-pyrrolidin-2-one; anhydrous phosphorus trichloride; chlorine; trichlorophosphate;
90%
With anhydrous phosphorus trichloride; chlorine; trichlorophosphate; In water;
81%
With tetraethylammonium chloride; trichlorophosphate; for 24h; Heating;
78%
With N,N-dimethyl-aniline; trichlorophosphate; at 110 ℃; for 10h; Inert atmosphere;
65%
With N-benzyl-N,N,N-triethylammonium chloride; trichlorophosphate; at 50 ℃; for 7h; Inert atmosphere;
56%
With trichlorophosphate; at 130 - 140 ℃;
With trichlorophosphate; at 180 ℃;
With N,N-dimethyl-aniline; trichlorophosphate;
With hydrogenchloride; anhydrous phosphorus trichloride; chlorine; triethylamine; trichlorophosphate;
With trichlorophosphate; In N,N-dimethyl-aniline;
5-ethyl-2-methyl-pyridine
104-90-5

5-ethyl-2-methyl-pyridine

BARBITURIC ACID
67-52-7,944357-77-1

BARBITURIC ACID

2,4,6-trichloropyrimidine
3764-01-0

2,4,6-trichloropyrimidine

Conditions
Conditions Yield
With anhydrous phosphorus trichloride; chlorine; trichlorophosphate;
96%

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