Pharmaceutical

106809-14-7

  • Product Name：2,4-Dichloro-5-fluoro-3-nitrobenzoic acid
  • Molecular Formula：C7H2Cl2FNO4
  • Specifications：99%
  • Molecular Weight：254.002
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Product Details;

CasNo： 106809-14-7

Molecular Formula： C7H2Cl2FNO4

Appearance： white to light yellow crystal powder

Reputable factory supply 2,4-Dichloro-5-fluoro-3-nitrobenzoic acid 106809-14-7 in bulk at low price

  • Molecular Formula:C7H2Cl2FNO4
  • Molecular Weight:254.002
  • Appearance/Colour:white to light yellow crystal powder 
  • Vapor Pressure:8.54E-07mmHg at 25°C 
  • Melting Point:193-197 °C(lit.) 
  • Boiling Point:390.4 °C at 760 mmHg 
  • PKA:1.51±0.24(Predicted) 
  • Flash Point:189.9 °C 
  • PSA：83.12000 
  • Density:1.789 g/cm3 
  • LogP:3.26210 

2,4-Dichloro-5-fluoro-3-nitrobenzoic acid(Cas 106809-14-7) Usage

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 25, p. 927, 1988 DOI: 10.1002/jhet.5570250343

General Description

2,4-Dichloro-5-fluoro-3-nitrobenzoic acid can be prepared from 2,4-dichloro-5-fluorobenzoic acid.

InChI:InChI=1/C7H2Cl2FNO4/c8-4-2(7(12)13)1-3(10)5(9)6(4)11(14)15/h1H,(H,12,13)/p-1

106809-14-7 Relevant articles

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106809-14-7 Process route

2,4-dichloro-5-fluoroacetophenone
704-10-9

2,4-dichloro-5-fluoroacetophenone

2,4-dichloro-5-fluoro-3-nitro-benzoic acid
106809-14-7

2,4-dichloro-5-fluoro-3-nitro-benzoic acid

Conditions
Conditions Yield
With sulfuric acid; nitric acid; at 103 - 110 ℃; for 3h; Temperature;
91%
With sulfuric acid; nitric acid; 1.) 55 deg C; 2.) 75 deg C, 3 h;
82%
sulfuric acid
7664-93-9

sulfuric acid

water
7732-18-5

water

2,4-dichloro-5-fluoro-benzoic acid
86522-89-6

2,4-dichloro-5-fluoro-benzoic acid

2,4-dichloro-5-fluoro-3-nitro-benzoic acid
106809-14-7

2,4-dichloro-5-fluoro-3-nitro-benzoic acid

Conditions
Conditions Yield
With nitric acid; In methanol; ice-water;
With nitric acid; In methanol; (2S)-N-methyl-1-phenylpropan-2-amine hydrate;
With nitric acid; In methanol; (2S)-N-methyl-1-phenylpropan-2-amine hydrate;

106809-14-7 Upstream products

  • 704-10-9
    704-10-9

    2,4-dichloro-5-fluoroacetophenone

  • 86522-89-6
    86522-89-6

    2,4-dichloro-5-fluoro-benzoic acid

  • 7664-93-9
    7664-93-9

    sulfuric acid

  • 7732-18-5
    7732-18-5

    water

106809-14-7 Downstream products

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    104600-29-5

    2,4-dichloro-5-fluoro-3-nitro-benzoyl chloride

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    138998-63-7

    ethyl 2-[(2,4-dichloro-5-fluoro-3-nitrophenyl)carbonyl]-3-(dimethylamino)prop-2-enoate

  • 111453-56-6
    111453-56-6

    ethyl 3-(N-cyclopropylamino)-2-(2,4-dichloro-5-fluoro-3-nitrobenzoyl) acrylate

  • 106809-15-8
    106809-15-8

    ethyl (2,4-dichloro-5-fluoro-3-nitrobenzoyl)acetate

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