Catalyst and Auxiliary

139-13-9

  • Product Name:Nitrilotriacetic acid
  • Molecular Formula:C6H9NO6
  • Specifications:99%
  • Molecular Weight:191.141
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Product Details;

CasNo: 139-13-9

Molecular Formula: C6H9NO6

Appearance: white powder

Perfect Factory Offer Excellent quality Nitrilotriacetic acid 139-13-9 with Safe Shipping

  • Molecular Formula:C6H9NO6
  • Molecular Weight:191.141
  • Appearance/Colour:white powder 
  • Vapor Pressure:0-0Pa at 20-25℃ 
  • Melting Point:246 ºC 
  • Refractive Index:1.4860 (estimate) 
  • Boiling Point:498.2 ºC at 760 mmHg 
  • PKA:3.03, 3.07, 10.70(at 20℃) 
  • Flash Point:255.1 ºC 
  • PSA:115.14000 
  • Density:1.61 g/cm3 
  • LogP:-1.45780 

Nitrilotriacetic acid(Cas 139-13-9) Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 15, p. 46, 1950 DOI: 10.1021/jo01147a008

Air & Water Reactions

Water Insoluble.

Reactivity Profile

Nitrilotriacetic acid is incompatible with strong oxidizers, aluminum, copper, copper alloy and nickel. Nitrilotriacetic acid is also incompatible with strong bases.

Hazard

Possible carcinogen.

Health Hazard

Toxicity and health hazard of these compounds are low. Contact with eyes causes irritation.

Fire Hazard

Flash point data for Nitrilotriacetic acid are not available; however, Nitrilotriacetic acid is probably combustible.

Flammability and Explosibility

Nonflammable

Biochem/physiol Actions

Nitrilotriacetic (NTA) has the ability to link with histidine side chain of proteins. It can be used in fluorescent labelling, hexahistidine (His6)-tagged proteins for purification and surface immobilization.

Safety Profile

Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx,.

Potential Exposure

Nitrilotriacetic acid (NTA) was used as a phosphate replacement in laundry detergents in the late 1960s. In 1971, the use of NTA was discontinued. The possibility of resumed use arose in 1980. NTA is now used in laundry detergents in states where phosphates are banned. NTA is also used as a boiler feed-water additive at a maximum use level of 5 ppm of trisodium salt. Currently, the remaining nondetergent uses of NTA are for water treatment, textile treatment; metal plating and cleaning; and pulp and paper processing.

Carcinogenicity

Nitrilotriacetic acid is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

Shipping

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Purification Methods

Crystallise it from water and dry it at 110o. [Beilstein 4 IV 2441.]

Incompatibilities

Dust may form explosive mixture with air. Compounds of the carboxyl group react with all bases, both inorganic and organic (i.e., amines) releasing substantial heat, water and a salt that may be harmful. Incompatible with arsenic compounds (releases hydrogen cyanide gas), diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides (releasing heat, toxic and possibly flammable gases), thiosulfates and dithionites (releasing hydrogen sulfate and oxides of sulfur). Attacks aluminum, copper, copper alloy and nickel.

Waste Disposal

Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.

General Description

Odorless white solid. Sinks in and mixes with water.

InChI:InChI=1/C6H9NO6/c8-4(9)1-7(2-5(10)11)3-6(12)13/h1-3H2,(H,8,9)(H,10,11)(H,12,13)

139-13-9 Relevant articles

-

Martell,Bersworth

, p. 46 (1950)

-

-

Ogata et al.

, p. 1107 (1968)

-

PROCESS TO PREPARE A CHELATING AGENT OR PRECURSOR THEREOF USING A CYANIDE SALT

-

Page/Page column 8-9, (2010/12/29)

The present invention relates to a proce...

Substrate and method for producing the substrate

-

, (2009/04/23)

To enable measurements having high S/N r...

Imaging of Enzyme Activity

-

, (2008/06/13)

This invention relates to biochemistry a...

Ultra-high specificity fluorescent labeling

-

, (2008/06/13)

A self-assembled relay probe for detecti...

139-13-9 Process route

N,N-dicarboxymethyl hydrazine
19247-05-3

N,N-dicarboxymethyl hydrazine

nitrilotriacetic acid
139-13-9,80751-51-5

nitrilotriacetic acid

glycine
56-40-6,18875-39-3,25718-94-9

glycine

Conditions
Conditions Yield
beim Erhitzen;
 
ammonia
7664-41-7

ammonia

chloroacetic acid
79-11-8

chloroacetic acid

nitrilotriacetic acid
139-13-9,80751-51-5

nitrilotriacetic acid

glycine
56-40-6,18875-39-3,25718-94-9

glycine

Conditions
Conditions Yield
 
 

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139-13-9 Downstream products

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    nitrilotriacetic acid tris(p-nitrophenyl ester)

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