Catalyst and Auxiliary

154992-24-2

  • Product Name：RU 58841
  • Molecular Formula：C17H18F3N3O3
  • Specifications：99%
  • Molecular Weight：369.343
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Product Details;

CasNo： 154992-24-2

Molecular Formula： C17H18F3N3O3

Excellent chemical plant bulk supply RU 58841 154992-24-2 We supply high quality RU 58841 (CAS 154992-24-2), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the RU 58841 ?

RU 58841 is , while it's Molecular Formula is C17H18F3N3O3. RU 58841, is a specific androgen receptor antagonist or anti-androgen, that has shown to have effect on hair growth.

What is the CAS number for RU 58841 ?

The CAS number of RU 58841 is 154992-24-2.

More information of RU 58841 154992-24-2 are:

Synonyms

 4-(4,4-Dimethyl-2,5-dioxo-3-(4-hydroxybutyl)1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile;4-[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-trifluoromethylbenzonitrile;RU 58841;

CAS Number

 154992-24-2

Molecular Formula

 C17H18F3N3O3

Molecular Weight

 369.343

Density

 1.397 g/cm3

Boiling Point

 493.588 °C at 760 mmHg

Flash Point

 252.313 °C

HS CODE

 2933990090

PSA

 84.64000

LogP

 2.89968

Pka

 15.09±0.10(Predicted)

What is RU 58841 (154992-24-2) used for?

RU-58841 is a non-steroidal antiandrogen that binds to the androgen receptor (Kd = 1.8, 1.1, 5.6, 1.3, and 1.4 nM for human, rat, mouse, hamster prostate, and hamster flank organ receptors, respectively). In vivo, topical administration of RU-58841 (1-100 μg per animal) reduces size of the flank organ without affecting sex organs in a dose-dependent manner in hamsters. It has no effect on sex organ weight in intact rats when administered percutaneously, subcutaneously, or orally at doses up to 1 mg per animal. RU-58841 (5% v/v) also induces hair regrowth in the bald frontal scalps of postpubertal stumptailed macaques, a model for male pattern baldness.

InChI:InChI=1/C17H18F3N3O3/c1-16(2)14(25)23(15(26)22(16)7-3-4-8-24)12-6-5-11(10-21)13(9-12)17(18,19)20/h5-6,9,24H,3-4,7-8H2,1-2H3

Articles related to RU 58841:

Article

Source

Alternative synthesis of the anti-baldness compound RU58841

Leonard, Matthew J.,Lingham, Anthony R.,Niere, Julie O.,Jackson, Neale R. C.,McKay, Peter G.,Huegel, Helmut M.

, p. 14143 - 14148 (2014/04/17)

Cosmetic or pharmaceutical compositions

-

, (2008/06/13)

How to get the best price on RU 58841?

Hebei Jinsheng Zhongtai Industrial Co., Ltd is a quality supplier and manufacturer of RU 58841 . You can buy high quality, low price RU 58841 154992-24-2 here. Contact us.

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