Pharmaceutical

59-92-7

  • Product Name:Levodopa
  • Molecular Formula:C9H11NO4
  • Specifications:99%
  • Molecular Weight:197.191
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Product Details;

CasNo: 59-92-7

Molecular Formula: C9H11NO4

Appearance: colorless crystalline powder

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What is the Levodopa ?

Levodopa is colorless crystalline powder, while it's Molecular Formula is C9H11NO4. Levodopa is an immediate precursor of dopamine and product of tyrosine hydroxylase. It derived from vanillin is widely used for treatment of Parkinson’s disease, most often in combination with peripheral decarboxylase inhibitors such as benserazide and carbidopa.

What is the CAS number for Levodopa ?

The CAS number of Levodopa is 59-92-7.

More information of Levodopa 59-92-7 are:

Synonyms

Syndopa;(-)-3-(3,4-Dihydroxyphenyl)-L-alanine;L-(o-Dihydroxyphenyl)alanine;Bendopa;Dopaston;Dopar (TN);Deadopa;Prodopa;.Beta.-(3,4-Dihydroxyphenyl)-L-alanine;Brocadopa;3-Hydroxy-L-tyrosine;Dopasol;3, 4-Dihydroxy-L-phenylalanine;Pardopa;Maipedopa;L-3,4-Dihydrophenylalanine;3-(3,4-Dithydroxyphenyl)-L-alanine;Dopal-Fher;L-o-Hydroxytyrosine;Component of Sinemet;Larodopa;Alanine, 3-(3, 4-dihydroxyphenyl)-, (-)-;Dopaflex;Levopa;L-dopa;L-.Beta.-(3,4-Dihydroxyphenyl)alanine;3,4-Dihydroxy-L-phenylalanine;Insulamina;L(-)-Dopa;Eldopal;L-Tyrosine,3-hydroxy-;Eldopar;Alanine, 3-(3,4-dihydroxyphenyl)-;Dopaston SE;Helfo-Dopa;Dopalina;L-DOPA LEVODOPA;

CAS Number

59-92-7

Molecular Formula

C9H11NO4

Molecular Weight

197.191

Density

1.468 g/cm3

Melting Point

276-278 °C(lit.)

Boiling Point

448.4 °C at 760 mmHg

Flash Point

225 °C

HS CODE

29225090

PSA

103.78000

LogP

0.75250

Pka

2.32(at 25℃)

What is Levodopa (59-92-7) used for?

Levodopa is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. When in the brain, levodopa is decarboxylated to dopamine and stimulates the dopaminergic receptors, thereby compensating for the depleted supply of endogenous dopamine seen in Parkinson's disease. To assure that adequate concentrations of levodopa reach the central nervous system, it is administered with carbidopa, a decarboxylase inhibitor that does not cross the blood-brain barrier, thereby diminishing the decarboxylation and inactivation of levodopa in peripheral tissues and increasing the delivery of dopamine to the CNS.

InChI:InChI=1/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1

Articles related to Levodopa:

Article

Source

New L-dopa codrugs as potential antiparkinson agents

Sozio, Piera,Iannitelli, Antonio,Cerasa, Laura Serafina,Cacciatore, Ivana,Cornacchia, Catia,Giorgioni, Gianfabio,Ricciutelli, Massimo,Nasuti, Cinzia,Cantalamessa, Franco,Di Stefano, Antonio

, p. 412 - 417 (2008)

Immobilization of polyphenol oxidase onto mesoporous activated carbons - isotherm and kinetic studies

John Kennedy,Selvi,Aruna Padmanabhan,Hema,Sekaran

, p. 262 - 270 (2007)

How to get the best price on Levodopa?

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