CasNo: 59-92-7
Molecular Formula: C9H11NO4
Appearance: colorless crystalline powder
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Levodopa is colorless crystalline powder, while it's Molecular Formula is C9H11NO4. Levodopa is an immediate precursor of dopamine and product of tyrosine hydroxylase. It derived from vanillin is widely used for treatment of Parkinson’s disease, most often in combination with peripheral decarboxylase inhibitors such as benserazide and carbidopa.
The CAS number of Levodopa is 59-92-7.
More information of Levodopa 59-92-7 are:
Synonyms |
Syndopa;(-)-3-(3,4-Dihydroxyphenyl)-L-alanine;L-(o-Dihydroxyphenyl)alanine;Bendopa;Dopaston;Dopar (TN);Deadopa;Prodopa;.Beta.-(3,4-Dihydroxyphenyl)-L-alanine;Brocadopa;3-Hydroxy-L-tyrosine;Dopasol;3, 4-Dihydroxy-L-phenylalanine;Pardopa;Maipedopa;L-3,4-Dihydrophenylalanine;3-(3,4-Dithydroxyphenyl)-L-alanine;Dopal-Fher;L-o-Hydroxytyrosine;Component of Sinemet;Larodopa;Alanine, 3-(3, 4-dihydroxyphenyl)-, (-)-;Dopaflex;Levopa;L-dopa;L-.Beta.-(3,4-Dihydroxyphenyl)alanine;3,4-Dihydroxy-L-phenylalanine;Insulamina;L(-)-Dopa;Eldopal;L-Tyrosine,3-hydroxy-;Eldopar;Alanine, 3-(3,4-dihydroxyphenyl)-;Dopaston SE;Helfo-Dopa;Dopalina;L-DOPA LEVODOPA; |
CAS Number |
59-92-7 |
Molecular Formula |
C9H11NO4 |
Molecular Weight |
197.191 |
Density |
1.468 g/cm3 |
Melting Point |
276-278 °C(lit.) |
Boiling Point |
448.4 °C at 760 mmHg |
Flash Point |
225 °C |
HS CODE |
29225090 |
PSA |
103.78000 |
LogP |
0.75250 |
Pka |
2.32(at 25℃) |
Levodopa is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. When in the brain, levodopa is decarboxylated to dopamine and stimulates the dopaminergic receptors, thereby compensating for the depleted supply of endogenous dopamine seen in Parkinson's disease. To assure that adequate concentrations of levodopa reach the central nervous system, it is administered with carbidopa, a decarboxylase inhibitor that does not cross the blood-brain barrier, thereby diminishing the decarboxylation and inactivation of levodopa in peripheral tissues and increasing the delivery of dopamine to the CNS.
InChI:InChI=1/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1
Articles related to Levodopa:
Article |
Source |
New L-dopa codrugs as potential antiparkinson agents |
Sozio, Piera,Iannitelli, Antonio,Cerasa, Laura Serafina,Cacciatore, Ivana,Cornacchia, Catia,Giorgioni, Gianfabio,Ricciutelli, Massimo,Nasuti, Cinzia,Cantalamessa, Franco,Di Stefano, Antonio , p. 412 - 417 (2008) |
Immobilization of polyphenol oxidase onto mesoporous activated carbons - isotherm and kinetic studies |
John Kennedy,Selvi,Aruna Padmanabhan,Hema,Sekaran , p. 262 - 270 (2007) |
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