Synthetic Flavours & Fragrances

93-16-3

  • Product Name：Methyl isoeugenol
  • Molecular Formula：C11H14O2
  • Specifications：99%
  • Molecular Weight：178.231
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Product Details;

CasNo： 93-16-3

Molecular Formula： C11H14O2

Manufacturer supply top purity Methyl isoeugenol 93-16-3 with ISO standards

  • Molecular Formula:C11H14O2
  • Molecular Weight:178.231
  • Vapor Pressure:0.011mmHg at 25°C 
  • Melting Point:98-100 °C(lit.) 
  • Refractive Index:n20/D 1.568(lit.)  
  • Boiling Point:271.1 °C at 760 mmHg 
  • Flash Point:104.5 °C 
  • PSA：18.46000 
  • Density:0.998 g/cm3 
  • LogP:2.73690 

Methyl isoeugenol(Cas 93-16-3) Usage

Preparation

By methylation of isoeugenol with methyl sulfate in alkaline solution

Toxicity evaluation

The acute oral LD50 in rats was reported as 1.5 g/kg (Jenner, Hagan, Taylor, Cook & Fitzhugh, 1964) and as 2.5 g/kg (2.03-3.08 g/kg) (Keating, 1972). The ip LD50 in mice was reported as 0.5 g/kg for the eis- isomer and as 0.35 g/kg for the trans- isomer (Caujolle & Meynier, 1960). The acute dermal LD50 in rabbits exceeded 5 g/kg (Keating, 1972)

General Description

Methyl isoeugenol is one of the main components found in the essential oil extracted from Acorus calamus, bark of Croton malambo and rhizomes of Zingiber zerumbet, Hedychium coronarium and Etlingera cevuga.

InChI:InChI=1/C11H14O2/c1-4-5-9-6-7-10(12-2)11(8-9)13-3/h4-8H,1-3H3/b5-4-

93-16-3 Relevant articles

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Design, synthesis and pharmacological evaluation of novel antiinflammatory and analgesic O-benzyloxime compounds derived from natural eugenol

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An isoeugenol 4-O-methyltransferase (IeO...

93-16-3 Process route

1,2-Dimethoxy-4-<3-fluoro-3-(phenylsulfonyl)-2-propenyl>benzene

1,2-Dimethoxy-4-<3-fluoro-3-(phenylsulfonyl)-2-propenyl>benzene

1,2-dimethoxy-4-(2-propenyl)benzene
93-15-2

1,2-dimethoxy-4-(2-propenyl)benzene

Z-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene
161436-14-2,161436-20-0

Z-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene

(E)-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene
161436-20-0

(E)-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene

Methylisoeugenol
93-16-3

Methylisoeugenol

Conditions
Conditions Yield
With disodium hydrogenphosphate; sodium amalgam; In tetrahydrofuran; methanol; at 25 ℃; for 0.333333h; Product distribution; various time, temp.;
29 % Chromat.
44 % Chromat.
17 % Chromat.
8 % Chromat.
1,2-dimethoxy-4-(2-propenyl)benzene
93-15-2

1,2-dimethoxy-4-(2-propenyl)benzene

Methylisoeugenol
93-16-3

Methylisoeugenol

Conditions
Conditions Yield
With potassium hydroxide; In butan-1-ol; for 12h; Reflux;
86%
With potassium carbonate;
With bis(cyclopentadienyl)titanium dichloride; ethylaluminum dichloride; magnesium; In tetrahydrofuran; at 0 - 22 ℃; for 72h; Inert atmosphere; Schlenk technique;
With [{RuCl(μ-Cl)(η3:η3-2,7-dimethylocta-2,6-diene-1,8-diyl)}2]; In methanol; water; at 80 ℃; for 1.5h;

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