Catalyst and Auxiliary

73-22-3

  • Product Name：L-Tryptophane
  • Molecular Formula：C11H12N2O2
  • Specifications：99%
  • Molecular Weight：204.228
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Product Details;

CasNo： 73-22-3

Molecular Formula： C11H12N2O2

Appearance： White to off-white crystalline powder

China cas 73-22-3 factory wholesale L-Tryptophane at affordable price

  • Molecular Formula:C11H12N2O2
  • Molecular Weight:204.228
  • Appearance/Colour:White to off-white crystalline powder 
  • Vapor Pressure:8.3E-09mmHg at 25°C 
  • Melting Point:289-290 °C (dec.)(lit.) 
  • Refractive Index:-32 ° (C=1, H2O) 
  • Boiling Point:447.908 °C at 760 mmHg 
  • Flash Point:224.687 °C 
  • PSA：79.11000 
  • Density:1.363 g/cm3 
  • LogP:1.82260 

L-Tryptophane(Cas 73-22-3) Usage

Essential Amino Acid

Tryptophan (TRP) is an essential amino acid in mammals, crucial for various physiological processes such as neuronal function, immunity, and gut homeostasis.

Chemical Structure and Classification

Tryptophan is the largest of the three aromatic amino acids, with a benzoic nucleus and a pyrrole ring in its side chain. It has the molecular formula C11H12N2O2 and is categorized as a glucogenic/ketogenic amino acid.

Dietary Sources and Absorption

Being essential, TRP must be obtained through the diet. Rich dietary sources include dairy products, eggs, meat, fish, and chocolate. After being released from dietary protein, TRP is absorbed through the intestinal epithelium into the systemic circulation, where intestinal microbiota further metabolizes it to indoles.

Physiological Effects

TRP serves as a precursor for metabolites that significantly affect various physiological functions, including gastrointestinal functions, immunity, metabolism, and the nervous system.

Binding and Regulation

In circulation, TRP is primarily bound to albumin, with only a small fraction being free. Plasma TRP levels are regulated by factors such as glucocorticoids, interferon-纬, glucose, nicotinamide, and antidepressants.

Implications in Neuropsychiatric and Neurodegenerative Disorders

Changes in circulating TRP levels can impact its availability for serotonin and melatonin synthesis in the brain, potentially contributing to the pathophysiology of various neuropsychiatric and neurodegenerative disorders.

Role in Cancer and Immunoregulation

TRP metabolism has been implicated in cancer-related processes, including anti-proliferative effects on tumor cells and cancer-related anorexia and cachexia. Research is ongoing regarding the immunoregulatory properties of IDO and its involvement in diseases such as autoimmunity, infection, and cancer.

General Description

L-Tryptophane is an essential amino acid that serves as a precursor for the synthesis of serotonin and melatonin, which play important roles in regulating mood and sleep. It is found in a variety of protein-rich foods such as turkey, chicken, fish, and dairy products, and is also available as a dietary supplement. L-Tryptophane has been studied for its potential therapeutic effects in treating depression, anxiety, and sleep disorders, and has also been investigated for its role in supporting immune function and promoting healthy digestion. However,

InChI:InChI=1/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1

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73-22-3 Process route

N-{(4-{methyl[(4-nitrophenoxy)carbonyl]amino}benzyloxy)carbonyl}-L-tryptophan
402943-23-1

N-{(4-{methyl[(4-nitrophenoxy)carbonyl]amino}benzyloxy)carbonyl}-L-tryptophan

4-nitro-phenol
100-02-7,78813-13-5,89830-32-0

4-nitro-phenol

carbon dioxide
124-38-9,18923-20-1

carbon dioxide

L-Tryptophan
73-22-3,27732-43-0,80206-30-0,27813-82-7

L-Tryptophan

(4-(methylamino)phenyl)methanol
181819-75-0

(4-(methylamino)phenyl)methanol

Conditions
Conditions Yield
With abzyme ST51; water; In dimethyl sulfoxide; at 25 ℃; pH=9.0; Further Variations:; time dependence; Enzyme kinetics;
water
7732-18-5

water

[5']adenylic acid L-tryptophan anhydride
31528-64-0

[5']adenylic acid L-tryptophan anhydride

5'-adenosine monophosphate
61-19-8,24937-83-5,67583-85-1

5'-adenosine monophosphate

L-Tryptophan
73-22-3,27732-43-0,80206-30-0,27813-82-7

L-Tryptophan

Conditions
Conditions Yield
at 37 ℃; Zeitlicher Verlauf in Loesung vom pH 7.2.Hydrolysis;

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